Depression is
associated with an increased risk for Parkinson’s disease, a new study
reports, and the more severe the depression, the higher the risk.
Swedish researchers
compared 140,688 people with depression with 421,943 controls without
the disorder.
They followed the group for an average of seven years, and
in some cases as long as 25 years, and found 3,260 cases of
Parkinson’s.
The study, in Neurology,
found that the rate of Parkinson’s disease among people with depression
was almost three times that of people without it.
Among people with
depression, those who were hospitalized and those whose depression was
recurrent were at higher risk, suggesting that the more severe the
depression the greater the risk.
The lead author of the
study, Peter Nordstrom, a professor of geriatrics at Umea University in
Sweden, said the effect is small and detectable only in a large
population, and that most people with depression will never get
Parkinson’s.
Whether depression is a risk factor for Parkinson’s or an
early symptom of the illness is unknown.
“It could be that
depression damages the brain, causing the increase in Parkinson’s,” Dr.
Nordstrom said.
“Or it could also be that very early in Parkinson’s, we
are more prone to depression. It’s impossible to say.”
From NY Times
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